At the Health Equity for Advancing Research and Technology using Genomic Neuroscience (HEART-GeN) lab, we study how small differences in our DNA change the way genes are read out in the brain – which RNA transcripts a cell makes, how they are regulated, and how this shifts across brain development, aging, schizophrenia, and dementia. By combining human brain tissue, stem cell models, genetics, and interpretable machine learning, we work to pin down the mechanisms behind these changes and to make sure the discoveries hold across the diverse populations they are meant to serve.
Dr. Benjamin offers consulting in omics analysis, with 5 years of experience supporting research projects and analytical workflows. Fees available upon request. Get in touch about consulting.
We’re excited to share our new preprint, “IsoGraph resolves coordinated transcript choice and gene abundance in the aging human brain,” now available on bioR...
We are excited to share a major milestone for our lab: our first preprint is now available on bioRxiv. The manuscript, “Local SNP-explained methylation vari...
On June 5, 2026, the HEART-GeN Lab had two reasons to celebrate Sula Perloff: she successfully passed her PhD qualifying exam, and it was also her birthday.
The HEART-GeN Lab is proud to congratulate Jalil Hemphill on being selected as the recipient of the Fletcher Prize for Rising Undergraduate Research Star.
On May 27, 2026, the HEART-GeN Lab gathered for a celebration that brought together several important moments for our team.
On May 26, 2026, the HEART-GeN Lab welcomed the inaugural cohort of the HEART-GeN Summer Scholar Program. The program was created to provide a structured, t...