HEART-GeN lab publications and pre-prints
Publications and Pre-prints
2024
Benjamin, KJM+, Arora, R+, Feltrin, AS, Pertea, G, Giles, H, Stolz, JM, D’Ignazio, L, Collado-Torres, L, Shin, JH, Hyde, TM, Kleinman, JE, Weinberger, DR, Paquola, ACM, and Jennifer A Erwin. “How sex affects transcriptional associations with schizophrenia across the dorsolateral prefrontal cortex, hippocampus, and caudate nucleus”. Nature Communications (Accepted). 2024. DOI: https://doi.org/10.1101/2022.09.30.22280452.
Benjamin, KJM, Chen, Q, Eagles, NJ, Huuki-Myers, LA, Collado-Torres, L, Stolz, JM, Shin, JH, Paquola, ACM, Hyde, TM, Kleinman, JE, Jaffe, AE, Han, S, and Daniel R Weinberger. “Genetic and environmental contributions to ancestry differences in gene expression in the human brain”. Nature Neuroscience (Accepted). 2024. PMID: 37034760.
2023
Benjamin, KJM, Katipalli, T and Apuã CM Paquola. “dRFEtools: dynamic recursive feature elimination for omics”. Bioinformatics. 2023. PMID: 37632789. PDF.
Sawada, T, Barbosa, A, Araujo, B, McCord, AE, D’Ignazio, L, Benjamin, KJM, Sheehan, B, Zabolocki, M, Feltrin, A, Arora, R, Brandtjen, A, Kleinman, JE, Hyde, TM, Bardy, C, Weinberger, DR, Paquola, ACM, and Jennifer A Erwin. “Recapitulation of perturbed striatal gene expression dynamics of donor’s brains with ventral forebrain organoids derived from the same individuals with schizophrenia”. American Journal of Psychiatry. 2023. PMID: 37915216.
2022
Benjamin, KJM, Chen, Q, Jaffe, AE, Stolz, JM, Collado-Torres, L, Huuki-Myers, LA, Burke, EE, Arora, R, Feltrin, AS, Barbosa, AR, Radulescu, E, Pergola, G, Shin, JH, Ulrich, WS, Deep-Soboslay, A, Tao, R, the BrainSeq Consortium, Hyde, TM, Kleinman, JE, Erwin, JA, Weinberger, DR, and Apuã CM Paquola. “Analysis of the caudate nucleus transcriptome in individuals with schizophrenia highlights effects of antipsychotics and novel risk genes”. Nature Neuroscience. 2022. PMID: 36319771. PDF.
D’Ignazio, L, Jacomini, RS, Qamar, B, Benjamin, KJM, Arora, R, Sawada, T, Diffenderfer, KE, Pankonin, AR, Hendriks, WT, Bragg, DC, Paquola, ACM, and Jennifer A Erwin. “Variation in TAF1 expression in female carrier induced pluripotent stem cells and human brain ontogeny has implications for adult neostriatum vulnerability in X-linked Dystonia Parkinsonism”. eNeuro. 2022. PMID: 35868859.
2020
Sawada, T, Benjamin, KJM, Brandtjen, AC, Tietze, E, Allen, SJ, Paquola, ACM, Kleinman, JE, Hyde, TM, and Jennifer A Erwin. “Generation of four postmortem dura-derived iPS cell lines from four control individuals with genotypic and brain-region-specific transcrptomic data available through the BrainSEQ consortium”. Stem Cell Research. 2020. PMID: 32446240.
Sawada, T, Chater, TE, Sasagawa, Y, Yoshimura, M, Fujimori, N, Tanaka, K, Benjamin, KJ, Paquola, ACM, Erwin, JA, Goda, Y, Nikaido, I, and Tadafumi Kato. “Developmental Excitation-Inhibition Imbalance Underlying Psychoses Revealed by Single-Cell Analyses of Discordant Twins-Derived Cerebral Organoids”. Molecular Psychiatry. 2020. PMID: 32764691.