About the HEART-GeN group
Dr. Benjamin’s Bio
Born and raised in a large extended family from Indianapolis, Indiana, Dr. Kynon Jade Benjamin is proud to be the first doctor in his family. Dr. Benjamin earned his GED with the support of his mother before moving on to Indiana University–Purdue University Indianapolis (IUPUI). At IUPUI, Dr. Benjamin completed his work study at a neuroscience research laboratory, which started his scientific research journey. In his predoctoral studies, Dr. Benjamin designed and implemented drug delivery and drug development assays as well as developed bioinformatic pipelines for differential expression analysis for Angelman syndrome - a neurodevelopmental disorder. In his subsequent postdoctoral fellowship at the Lieber Institute for Brain Development and Johns Hopkins University School of Medicine, he developed computational pipelines for large-scale transcriptional (bulk and single-cell), genetic, and functional associations analyses in postmortem brain and brain (i.e., cerebral and striatal) organoids.
Throughout his research career, Dr. Benjamin’s experiences have reinforced the importance of supporting others and fostering collaborative environments. As such, he has worked to provide mentorship, serve as a role model, and advocate for opportunities for others.
Research program
The primary goal of our research is to improve therapeutics for under-research communities (i.e., personalized medicine) by investigating the influence of genetic ancestry on neurological disorders in relevant tissues. To this end, we use and develop computational tools to examine the role of genetic ancestry in the brain. In addition to this, we have established collaborations to use computational tools to address hypothesize driven question with publically available single-cell and bulk tissues.
Our Team
Kynon Jade M. Benjamin (he/him)
Principal Investigator
Current Trainees
O. Sula Perloff (she/her)
Graduate Student (DGP)
Alzheimer's Research
Javier Hernandez (he/him)
Undergraduate
Gene-Gene Networks with VAEs
Elisa Johnson (she/her)
Undergraduate
DNAm and heritability
Yiju Choi (she/her)
Undergraduate
Functional Annotation (Genetic Ancestry)
Alumni
Sierra Mannion (she/her)
Undergraduate (URAP 2024-2025)
Local-Ancestry Aware xQTL
Jocelyn Wang (she/they)
Undergraduate (URAP 2024-2025)
Local-Ancestry Aware xQTL
Emma Tsai (she/her)
Undergraduate (SROP 2025)
Suicide and Schizophrenia
Louisiana State University
Nia Terry (she/her)
Undergraduate (SROP 2025)
DNAm Epigenetic Clocks (Schizophrenia)
Spelman College
Amirah Collins (she/her)
Undergraduate (BU 2025)
Shiny App for Transcriptomics
Research Staff
Christina Spaulding (she/her)
Lab Research Manager
Alexis Bennett (she/her)
Research Data Analyst
Manuel Hurtado, Jr. (he/him)
Research Data Analyst
Valentine Gilson (she/her)
Administrative